PHENYL PHOSPHONIUM CHLORIDE

PHENYL PHOSPHONIUM CHLORIDE - Names and Identifiers

Name	2-(trime-silyl)ethoxymethyl-triphenyl-phosphonium chloride
Synonyms	PHENYL PHOSPHONIUM CHLORIDE SEM-TRIPHENYLPHOSPHONIUM CHLORIDE [2-(trimethylsily)ethoxymethyl]triphenylphosphonium.Cl 2-(trime-silyl)ethoxymethyl-triphenyl-phosphonium chloride 2-(TRIMETHYLSILYL)ETHOXYMETHYLTRIPHENYLPHOSPHONIUM CHLORIDE -(Trimethylsilyl)ethoxymethyl-triphenylphosphonium chloride 2-(Trimethylsilyl)ethoxymethyl-triphenylphosphonium chloride,SEM-triphenylphosphonium chloride
CAS	82495-75-8
InChI	InChI=1/C24H30OPSi.ClH/c1-27(2,3)20-19-25-21-26(22-13-7-4-8-14-22,23-15-9-5-10-16-23)24-17-11-6-12-18-24;/h4-18H,19-21H2,1-3H3;1H/q+1;/p-1

PHENYL PHOSPHONIUM CHLORIDE - Physico-chemical Properties

Molecular Formula	C24H30ClOPSi
Molar Mass	429.01
Melting Point	145-149°C(lit.)
Solubility	Sol H2O and dichloromethane; sparingly soluble inTHF.
Appearance	powder to crystal
Color	White to Almost white
BRN	4632507
Storage Condition	Sealed in dry,2-8°C
MDL	MFCD00043159

PHENYL PHOSPHONIUM CHLORIDE - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3
FLUKA BRAND F CODES	3

PHENYL PHOSPHONIUM CHLORIDE - Introduction

2-(trime-silyl)ethoxymethyl-triphenyl-phosphonium chloride is an organic compound with the chemical formula [(C6H5)3 PCH2CH2OCH2Si(CH3)3]Cl.

properties: 2-(trime-silyl)ethoxymethyl-triphenyl-phosphonium chloride is a solid substance, generally white crystal. It has a relatively low melting and boiling point and is soluble in organic solvents such as ethanol, dimethylformamide and chlorinated hydrocarbons. The compound has high stability and storage properties.

Purpose: 2-(trime-silyl)ethoxymethyl-triphenyl-phosphonium chloride is widely used in organic synthesis. It can be used as a reagent for phosphating reactions, such as for reductive desilication of carbonyl compounds, deoxygenation protecting groups, etc. In addition, it can also be used as a ligand for transition metal-catalyzed reactions, such as olefin activation and allylation in organic synthesis.

Preparation Method: The 2-(trime-silyl)ethoxymethyl-triphenyl-phosphonium chloride can be prepared by a chemical synthesis method. A commonly used method is to react triphenylmethanol with trimethylsilyl ethanol to give 2-(trimethylsilyl) ethoxytrityl ether, which then reacts with tribromomethane to produce the target product.

Safety Information: 2-(trime-silyl)ethoxymethyl-triphenyl-phosphonium chloride is safe to use under normal experimental conditions. However, it is an irritating and toxic compound and should be avoided in contact with the skin, eyes and respiratory tract. Personal protective equipment should be worn during use and ensure that it is operated in a well-ventilated area.

Last Update：2024-04-10 22:29:15